Medicine


The Complete Guide to Taking Cialis

Main Data About Cialis

The name "Cialis" is familiar to a lot of men, especially since this drug is not new and is very popular, and not only in the United States. Cialis is the second most popular drug for combating erectile dysfunction in the world. It is second only to Viagra in terms of sales.

However, this is only the most basic information about Cialis. Men who are faced with such an unpleasant state of the body as a violation of potency, most likely, will be interested in learning more about this medicine - how it works and what it is, to whom it is recommended and whom not, how and where it can be purchased, and much more. That's what this article will be about.

Drug Name: Generic Cialis
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Composition of Cialis And How It Works

The main ingredient in Cialis is Tadalafil. This substance is of artificial origin, it was synthesized by scientists specifically for the purpose of creating an effective remedy for restoring potency, while having a minimum number of side effects.

Tadalafil is a reversible selective PDE-5 inhibitor. PDE-5 (phosphodiesterase type 50) is an enzyme found in the smooth muscles of the cavernous bodies of the penis, in the smooth muscles of the vessels of internal organs, to a lesser extent in skeletal muscles, platelets, kidneys, lungs, and cerebellum. When sexual arousal causes a local release of nitric oxide (in the tissues of the penis), inhibition of PDE5 by Tadalafil leads to an increase in the level of cGMP in cavernous bodies of the penis. Tadalafil acts mainly on PDE-5 in the vessels of the penis, to a lesser extent affecting the vessels of the lungs. It is some influence on the latter that causes a number of the most common side effects of Cialis, such as dizziness and flushing of the skin of the face.

Increase in the level of cGMP results in relaxation of the smooth muscles of the arteries, their dilation and increased blood flow to the tissues of the penis, which contributes to the onset of a strong erection. It should be remembered that Tadalafil is ineffective in the absence of sexual stimulation or sexual desire, since this medicine doesn't have any effect on the hormonal system of a man and doesn't have a stimulating effect of a narcotic nature. Cialis is not an aphrodisiac either.

In addition to Tadalafil, Cialis contains a number of other components, but they all refer to excipients: lactose monohydrate, magnesium stearate, etc. They do not have the slightest significant effect on a man's body. Their main and only purpose is to serve as a kind of substrate for the active substance, its container, to provide the mass and density of the pill.

Dosage And Release Forms

Cialis is available in pill form for oral administration. They have an oval shape, orange color, they can be easily cut with a sharp knife, but don't crumble. One pill may contain 5, 10 or 20 mg of Tadalafil. Branded Cialis has only one release form - pills, but its analogues, aka generics, may be produced in different forms, like sachets and soft chewable pills.

How To Take Cialis

The dosage regimen of Cialis is prescribed by the doctor depending on the individual case of the patient's disease. However, there are an extremely large number of men who themselves decide to resort to this medication without consulting a doctor. In order not to make a mistake in self-treatment, which is not very recommended, but which cannot be eradicated, the following information should be taken into account.

Cialis can be taken on demand, that is, a short time before the planned sexual intercourse, or on an ongoing basis, that is, in courses every day. This drug is effective against both erectile dysfunction (ED) of psychogenic etiology and against ED of physiological etiology. In addition, Cialis is successfully used in the treatment of ED of combined etiology. These features of Cialis make it the drug of choice for the treatment of erectile dysfunction in a huge number of men.

It should be noted that Cialis is the only drug on the modern pharmaceutical market from the group of PDE-5 inhibitors, which is not only approved for use in men with benign prostatic hyperplasia (BPH), but is also recommended as a treatment for this pathological condition. FDA approved the use of Tadalafil for this purpose in 2012 after a series of special clinical studies conducted by the manufacturer of Cialis, pharmaceutical company Eli Lilly, especially on this subject. Taking into account the fact that BPH is very often accompanied by erectile dysfunction, Cialis is a real lifesaver for men with prostate adenoma. The low severity of side effects makes this drug the optimal choice for older men, in whose age group BPH is most common.

If the symptoms of erectile dysfunction (too weak erection or inability to achieve it) bother you not too often and appear mainly with general fatigue, depressed mood, after a hard day at work, then the most suitable dosage for you would be 10 mg of Tadalafil, taken about half an hour before sex. A nice feature of Cialis is that this medicine can be taken with any amount of any food, since it does not affect the rate and degree of absorption of Tadalafil into the blood and, therefore, its effect. Cialis can be combined with even a small amount of alcohol. The main thing here is not to get carried away beyond measure, it is not recommended to drink more than a couple of glasses of wine in order to avoid excessive stress on the cardiovascular system.

Cialis is considered by scientific society literally the best remedy for combating stress impotence - this is an old term for ED provoked by stress factors. More data on how potency and psychology are connected can be found in the article "Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study" by Feldman H. A., Goldstein I., Hatzichristou D. G., et al.

If the symptoms of erectile dysfunction are manifested quite regularly, but you believe that they are caused by psychological problems, such as self-doubt or unpleasant sexual experiences, as well as a change of sexual partner, then you can take Cialis on a daily basis. One course ranges from two weeks to three months. In most cases, this is enough to normalize sex life, if a man does not have physiological problems with potency, and they are limited only by what is going on in his head. For daily use, a dosage of 5 mg of Tadalafil is most appropriate. Despite the fact that 5 mg is the minimum available dosage in one pill, with daily use, Tadalafil accumulates in the body, since one pill lasts up to 36 hours. As a result, even half of such a pill a day is enough for some men to feel ready for sexual exploits at any time of the day or night.
With severe erectile dysfunction, which is based on physiological reasons or their combination with psychological ones, as a rule, a dosage of 20 mg of Tadalafil before intercourse works best.

Men with BPH should consult an urologist before using Cialis, especially if they are already taking any medications for the treatment of prostate adenoma. Medicines should not conflict with each other. Usually, with BPH, the doctors prescribe a long-term intake of Cialis on a daily basis at a dosage of 5 mg. Tadalafil helps to normalize blood circulation not only in the penis, but also in all male reproductive organs, including the prostate gland, which helps to reduce its volume and normalize the outflow of prostate secretions. And an improvement in potency and, as a consequence, an increase in the frequency of sexual life or masturbation, contribute to the natural cleansing of the ducts of the prostate gland.

Buying Cialis Online

In the third decade of the twenty-first century, it is strange to rely only on local pharmacies when it comes to buying drugs, especially as expensive as Cialis. It is significantly more profitable to buy this medicine online than in regular pharmacies, especially for US residents. However, residents of other countries are also happy to use the services of online pharmacies - from those located in their home countries to foreign and international ones. Distances are no longer a problem when buying Cialis, especially since this medicine does not require any special transportation conditions, except for observing a temperature regime not higher than 25 degrees Celsius.

In order to buy Cialis online safely, not facing counterfeits or dubious manufacturers, it is needed to pay attention to the availability of the current license number for the sale of medicines on the Internet pharmacy website. Also, the payment form page on the website must have an encrypted connection. This is a guarantee that your money will reach the addressee.

In general, the process of purchasing Cialis in online pharmacies is no different from making any purchase in a regular online store. And to find the best price offer, you can use special websites - aggregators that perform the function of a search engine for online pharmacies with the highest rating based on consumer reviews.
A separate point that deserves attention when buying Cialis online is that in most online pharmacies this medicine can be purchased without a doctor's prescription, while in local pharmacies you won't get it over the counter, at least in the US.

Generic Cialis

The manufacturer of Cialis received a patent for it in 2002, when Tadalafil was approved by FDA (Food and Drug Administration). The patent holder was the American pharmaceutical company Eli Lilly. Nevertheless, the patent protection for this drug expired back in 2017 (in some countries - in 2018), and since then, not only the original Cialis, but also its generics have been available to consumers.

Generics differ from branded drugs in that their manufacturers are other pharmaceutical companies located in different countries of the world. Generics of Cialis are sold under other names such as Tadalafil, Generic Cialis, Generic Tadalafil, Tadalis and many others. All of them are united by the fact that their active ingredient is Tadalafil, usually its dosage also coincides with that in the brand name medicine. The appearance of Cialis generics varies greatly, they are not always oval yellow or orange tablets. Their color and shape may vary, as may the packaging. These parameters, of course, don't affect the effect of the medicine.

The best cheap generics of Cialis are, according to both experts and a large number of consumers, medicines produced in India. Tadalafil produced by Indian pharmaceutical companies is characterized by the most affordable cost combined with surprisingly high quality. Also, a good price/quality ratio is observed for Cialis from Canadian, Malay and Hungarian manufacturers.

In order to buy generic Cialis at best price, it should be borne in mind that in most major international online pharmacies, the price of this medicine is inversely proportional to the number of pills purchased. That is, the more Cialis pills you buy, the cheaper each one costs you. This is true for both branded drugs and generics.
A distinctive feature of Cialis generics is that, in addition to traditional pills, they are available in the form of sachets and soft tablets. It would seem, what is the point of these forms of drug release, if they are also intended for oral administration? Everything is very simple. The sachets begin to act much faster than conventional pills, and are optimal for situations where you need to achieve an erection as quickly as possible. This is possible due to the fact that Tadalafil is absorbed into the body faster, since this process begins already in the oral cavity. And soft tablets that you dissolve or chew are great when you need to take the medicine in secret from your partner, who will never know what kind of lollipop or mint candy you ate. In addition, both of these forms of release of Cialis are very popular among men who are negative about taking any pills for psychological reasons. Some people dislike feeling ill and prefer sachets and soft tablets for this very reason.